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KMID : 0882420130850010096
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Korean Journal of Medicine
2013 Volume.85 No. 1 p.96 ~ p.100
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Precursor B-Cell Acute Lymphoblastic Leukemia in Two Patients with a History of Cytotoxic Therapy
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Shin Suk-Pyo
Song Sang-Hee
Ko Eun-Jung
Kim Ji-Su
Park Chi-Young
Oh Do-Yeun
Chong So-Young
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Abstract
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Therapy-related myeloid neoplasms have been well characterized. However, precursor B-cell acute lymphoblastic leukemia in patients with prior malignancies is uncommon, and the effect of prior cytotoxic therapy on development of precursor B-cell acute lymphoblastic leukemia is controversial. Therapy-related precursor B-cell acute lymphoblastic leukemia has been reported occasionally. However, cytotoxic therapy-related precursor B-cell acute lymphoblastic leukemia has been reported in Korea only rarely. We herein describe two cases of therapy-related precursor B-cell acute lymphoblastic leukemia.
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KEYWORD
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Precursor B-cell acute lymphoblastic leukemia, Cytotoxic therapy, Therapy-related leukemia
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